Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Identifieur interne : 003C67 ( Main/Exploration ); précédent : 003C66; suivant : 003C68Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Auteurs : Violette Da Cunha [France] ; Mark R. Davies [Royaume-Uni, Australie] ; Pierre-Emmanuel Douarre [France] ; Isabelle Rosinski-Chupin [France] ; Immaculada Margarit [Italie] ; Sebastien Spinali [France] ; Tim Perkins [Italie] ; Pierre Lechat [France] ; Nicolas Dmytruk [France] ; Elisabeth Sauvage [France] ; Laurence Ma [France] ; Benedetta Romi [Italie] ; Magali Tichit [France] ; Maria-José Lopez-Sanchez [France] ; Stéphane Descorps-Declere [France] ; Erika Souche [France] ; Carmen Buchrieser [France] ; Patrick Trieu-Cuot [France] ; Ivan Moszer [France] ; Dominique Clermont [France] ; Domenico Maione [Italie] ; Christiane Bouchier [France] ; David J. Mcmillan [Australie] ; Julian Parkhill [Royaume-Uni] ; John L. Telford [Italie] ; Gordan Dougan [Royaume-Uni] ; Mark J. Walker [Australie] ; Matthew T. G. Holden [Royaume-Uni] ; Claire Poyart [France] ; Philippe Glaser [France]Source :
- Nature communications [ 2041-1723 ] ; 2014.
Descripteurs français
- KwdFr :
- Amérique du Nord (épidémiologie), Antibactériens (pharmacologie), Clones cellulaires, Données de séquences moléculaires, Europe (épidémiologie), Gènes bactériens, Génome bactérien, Humains, Infections à streptocoques (microbiologie), Infections à streptocoques (traitement médicamenteux), Infections à streptocoques (épidémiologie), Phylogénie, Polymorphisme de nucléotide simple, Résistance à la tétracycline (), Résistance à la tétracycline (génétique), Streptococcus agalactiae (), Streptococcus agalactiae (génétique), Streptococcus agalactiae (isolement et purification), Sélection génétique, Séquence nucléotidique, Séquençage nucléotidique à haut débit, Tétracycline (pharmacologie), Éléments transposables d'ADN.
- MESH :
- génétique : Résistance à la tétracycline, Streptococcus agalactiae.
- isolement et purification : Streptococcus agalactiae.
- microbiologie : Infections à streptocoques.
- pharmacologie : Antibactériens, Tétracycline.
- traitement médicamenteux : Infections à streptocoques.
- épidémiologie : Amérique du Nord, Europe, Infections à streptocoques.
- Clones cellulaires, Données de séquences moléculaires, Gènes bactériens, Génome bactérien, Humains, Phylogénie, Polymorphisme de nucléotide simple, Résistance à la tétracycline, Streptococcus agalactiae, Sélection génétique, Séquence nucléotidique, Séquençage nucléotidique à haut débit, Éléments transposables d'ADN.
English descriptors
- KwdEn :
- Anti-Bacterial Agents (pharmacology), Base Sequence, Clone Cells, DNA Transposable Elements, Europe (epidemiology), Genes, Bacterial, Genome, Bacterial, High-Throughput Nucleotide Sequencing, Humans, Molecular Sequence Data, North America (epidemiology), Phylogeny, Polymorphism, Single Nucleotide, Selection, Genetic, Streptococcal Infections (drug therapy), Streptococcal Infections (epidemiology), Streptococcal Infections (microbiology), Streptococcus agalactiae (classification), Streptococcus agalactiae (drug effects), Streptococcus agalactiae (genetics), Streptococcus agalactiae (isolation & purification), Tetracycline (pharmacology), Tetracycline Resistance (drug effects), Tetracycline Resistance (genetics).
- MESH :
- chemical , pharmacology : Anti-Bacterial Agents, Tetracycline.
- geographic , epidemiology : Europe, North America.
- classification : Streptococcus agalactiae.
- drug effects : Streptococcus agalactiae, Tetracycline Resistance.
- drug therapy : Streptococcal Infections.
- epidemiology : Streptococcal Infections.
- genetics : Streptococcus agalactiae, Tetracycline Resistance.
- isolation & purification : Streptococcus agalactiae.
- microbiology : Streptococcal Infections.
- Base Sequence, Clone Cells, DNA Transposable Elements, Genes, Bacterial, Genome, Bacterial, High-Throughput Nucleotide Sequencing, Humans, Molecular Sequence Data, Phylogeny, Polymorphism, Single Nucleotide, Selection, Genetic.
Abstract
Url:
DOI: 10.1038/ncomms5544
PubMed: 25088811
PubMed Central: 4538795
Affiliations:
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Le document en format XML
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Davies</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland</wicri:regionArea><wicri:noRegion>4072 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Douarre, Pierre Emmanuel" sort="Douarre, Pierre Emmanuel" uniqKey="Douarre P" 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nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Margarit, Immaculada" sort="Margarit, Immaculada" uniqKey="Margarit I" first="Immaculada" last="Margarit">Immaculada Margarit</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Spinali, Sebastien" sort="Spinali, Sebastien" uniqKey="Spinali S" first="Sebastien" last="Spinali">Sebastien Spinali</name><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, 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wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Dmytruk, Nicolas" sort="Dmytruk, Nicolas" uniqKey="Dmytruk N" first="Nicolas" last="Dmytruk">Nicolas Dmytruk</name><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" 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type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Ma, Laurence" sort="Ma, Laurence" uniqKey="Ma L" first="Laurence" last="Ma">Laurence Ma</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Romi, Benedetta" sort="Romi, Benedetta" uniqKey="Romi B" first="Benedetta" last="Romi">Benedetta Romi</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Tichit, Magali" sort="Tichit, Magali" uniqKey="Tichit M" first="Magali" last="Tichit">Magali Tichit</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Lopez Sanchez, Maria Jose" sort="Lopez Sanchez, Maria Jose" uniqKey="Lopez Sanchez M" first="Maria-José" last="Lopez-Sanchez">Maria-José Lopez-Sanchez</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Descorps Declere, Stephane" sort="Descorps Declere, Stephane" uniqKey="Descorps Declere S" first="Stéphane" last="Descorps-Declere">Stéphane Descorps-Declere</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Souche, Erika" sort="Souche, Erika" uniqKey="Souche E" first="Erika" last="Souche">Erika Souche</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Buchrieser, Carmen" sort="Buchrieser, Carmen" uniqKey="Buchrieser C" first="Carmen" last="Buchrieser">Carmen Buchrieser</name><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur, Biologie des Bactéries Intracellulaires, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Biologie des Bactéries Intracellulaires, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Trieu Cuot, Patrick" sort="Trieu Cuot, Patrick" uniqKey="Trieu Cuot P" first="Patrick" last="Trieu-Cuot">Patrick Trieu-Cuot</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A10">CNRS ERL3526, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS ERL3526, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Moszer, Ivan" sort="Moszer, Ivan" uniqKey="Moszer I" first="Ivan" last="Moszer">Ivan Moszer</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Clermont, Dominique" sort="Clermont, Dominique" uniqKey="Clermont D" first="Dominique" last="Clermont">Dominique Clermont</name><affiliation wicri:level="1"><nlm:aff id="A11">Institut Pasteur, Collection de l’Institut Pasteur (CIP), Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Collection de l’Institut Pasteur (CIP), Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Maione, Domenico" sort="Maione, Domenico" uniqKey="Maione D" first="Domenico" last="Maione">Domenico Maione</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Bouchier, Christiane" sort="Bouchier, Christiane" uniqKey="Bouchier C" first="Christiane" last="Bouchier">Christiane Bouchier</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Mcmillan, David J" sort="Mcmillan, David J" uniqKey="Mcmillan D" first="David J." last="Mcmillan">David J. Mcmillan</name><affiliation wicri:level="1"><nlm:aff id="A12">QIMR Berghofer Medical Research Institute, Brisbane, 7006 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, 7006 Queensland</wicri:regionArea><wicri:noRegion>7006 Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Inflammation and Healing Research Cluster, University of the Sunshine Coast, Sippy Downs, 4556 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Inflammation and Healing Research Cluster, University of the Sunshine Coast, Sippy Downs, 4556 Queensland</wicri:regionArea><wicri:noRegion>4556 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Parkhill, Julian" sort="Parkhill, Julian" uniqKey="Parkhill J" first="Julian" last="Parkhill">Julian Parkhill</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Telford, John L" sort="Telford, John L" uniqKey="Telford J" first="John L." last="Telford">John L. Telford</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Dougan, Gordan" sort="Dougan, Gordan" uniqKey="Dougan G" first="Gordan" last="Dougan">Gordan Dougan</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Mark J" sort="Walker, Mark J" uniqKey="Walker M" first="Mark J." last="Walker">Mark J. Walker</name><affiliation wicri:level="1"><nlm:aff id="A5">Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland</wicri:regionArea><wicri:noRegion>4072 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Holden, Matthew T G" sort="Holden, Matthew T G" uniqKey="Holden M" first="Matthew T. G." last="Holden">Matthew T. G. Holden</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A14">Institut Cochin, Université Sorbonne Paris Descartes, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Cochin, Université Sorbonne Paris Descartes, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A15">INSERM, U1016, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1016, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Glaser, Philippe" sort="Glaser, Philippe" uniqKey="Glaser P" first="Philippe" last="Glaser">Philippe Glaser</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25088811</idno><idno type="pmc">4538795</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538795</idno><idno type="RBID">PMC:4538795</idno><idno type="doi">10.1038/ncomms5544</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002D87</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D87</idno><idno type="wicri:Area/Pmc/Curation">002C37</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C37</idno><idno type="wicri:Area/Pmc/Checkpoint">001784</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001784</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">003531</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003531</idno><idno type="wicri:Area/PubMed/Curation">003418</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003418</idno><idno type="wicri:Area/PubMed/Checkpoint">003418</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003418</idno><idno type="wicri:Area/Ncbi/Merge">001C89</idno><idno type="wicri:Area/Ncbi/Curation">001C89</idno><idno type="wicri:Area/Ncbi/Checkpoint">001C89</idno><idno type="wicri:Area/Main/Merge">003D18</idno><idno type="wicri:Area/Main/Curation">003C67</idno><idno type="wicri:Area/Main/Exploration">003C67</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main"><italic>Streptococcus agalactiae</italic> clones infecting humans were selected and fixed through the extensive use of tetracycline</title><author><name sortKey="Da Cunha, Violette" sort="Da Cunha, Violette" uniqKey="Da Cunha V" first="Violette" last="Da Cunha">Violette Da Cunha</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Davies, Mark R" sort="Davies, Mark R" uniqKey="Davies M" first="Mark R." last="Davies">Mark R. Davies</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland</wicri:regionArea><wicri:noRegion>4072 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Douarre, Pierre Emmanuel" sort="Douarre, Pierre Emmanuel" uniqKey="Douarre P" first="Pierre-Emmanuel" last="Douarre">Pierre-Emmanuel Douarre</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Rosinski Chupin, Isabelle" sort="Rosinski Chupin, Isabelle" uniqKey="Rosinski Chupin I" first="Isabelle" last="Rosinski-Chupin">Isabelle Rosinski-Chupin</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Margarit, Immaculada" sort="Margarit, Immaculada" uniqKey="Margarit I" first="Immaculada" last="Margarit">Immaculada Margarit</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Spinali, Sebastien" sort="Spinali, Sebastien" uniqKey="Spinali S" first="Sebastien" last="Spinali">Sebastien Spinali</name><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Perkins, Tim" sort="Perkins, Tim" uniqKey="Perkins T" first="Tim" last="Perkins">Tim Perkins</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Lechat, Pierre" sort="Lechat, Pierre" uniqKey="Lechat P" first="Pierre" last="Lechat">Pierre Lechat</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Dmytruk, Nicolas" sort="Dmytruk, Nicolas" uniqKey="Dmytruk N" first="Nicolas" last="Dmytruk">Nicolas Dmytruk</name><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Sauvage, Elisabeth" sort="Sauvage, Elisabeth" uniqKey="Sauvage E" first="Elisabeth" last="Sauvage">Elisabeth Sauvage</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Ma, Laurence" sort="Ma, Laurence" uniqKey="Ma L" first="Laurence" last="Ma">Laurence Ma</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Romi, Benedetta" sort="Romi, Benedetta" uniqKey="Romi B" first="Benedetta" last="Romi">Benedetta Romi</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Tichit, Magali" sort="Tichit, Magali" uniqKey="Tichit M" first="Magali" last="Tichit">Magali Tichit</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Lopez Sanchez, Maria Jose" sort="Lopez Sanchez, Maria Jose" uniqKey="Lopez Sanchez M" first="Maria-José" last="Lopez-Sanchez">Maria-José Lopez-Sanchez</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Descorps Declere, Stephane" sort="Descorps Declere, Stephane" uniqKey="Descorps Declere S" first="Stéphane" last="Descorps-Declere">Stéphane Descorps-Declere</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Souche, Erika" sort="Souche, Erika" uniqKey="Souche E" first="Erika" last="Souche">Erika Souche</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Buchrieser, Carmen" sort="Buchrieser, Carmen" uniqKey="Buchrieser C" first="Carmen" last="Buchrieser">Carmen Buchrieser</name><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur, Biologie des Bactéries Intracellulaires, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Biologie des Bactéries Intracellulaires, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Trieu Cuot, Patrick" sort="Trieu Cuot, Patrick" uniqKey="Trieu Cuot P" first="Patrick" last="Trieu-Cuot">Patrick Trieu-Cuot</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A10">CNRS ERL3526, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS ERL3526, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Moszer, Ivan" sort="Moszer, Ivan" uniqKey="Moszer I" first="Ivan" last="Moszer">Ivan Moszer</name><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Clermont, Dominique" sort="Clermont, Dominique" uniqKey="Clermont D" first="Dominique" last="Clermont">Dominique Clermont</name><affiliation wicri:level="1"><nlm:aff id="A11">Institut Pasteur, Collection de l’Institut Pasteur (CIP), Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Collection de l’Institut Pasteur (CIP), Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Maione, Domenico" sort="Maione, Domenico" uniqKey="Maione D" first="Domenico" last="Maione">Domenico Maione</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Bouchier, Christiane" sort="Bouchier, Christiane" uniqKey="Bouchier C" first="Christiane" last="Bouchier">Christiane Bouchier</name><affiliation wicri:level="1"><nlm:aff id="A8">Institut Pasteur Genomic platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur Genomic platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Mcmillan, David J" sort="Mcmillan, David J" uniqKey="Mcmillan D" first="David J." last="Mcmillan">David J. Mcmillan</name><affiliation wicri:level="1"><nlm:aff id="A12">QIMR Berghofer Medical Research Institute, Brisbane, 7006 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, 7006 Queensland</wicri:regionArea><wicri:noRegion>7006 Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Inflammation and Healing Research Cluster, University of the Sunshine Coast, Sippy Downs, 4556 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Inflammation and Healing Research Cluster, University of the Sunshine Coast, Sippy Downs, 4556 Queensland</wicri:regionArea><wicri:noRegion>4556 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Parkhill, Julian" sort="Parkhill, Julian" uniqKey="Parkhill J" first="Julian" last="Parkhill">Julian Parkhill</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Telford, John L" sort="Telford, John L" uniqKey="Telford J" first="John L." last="Telford">John L. Telford</name><affiliation wicri:level="1"><nlm:aff id="A6">Novartis Vaccines and Diagnostics, Siena 53100, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Novartis Vaccines and Diagnostics, Siena 53100</wicri:regionArea><wicri:noRegion>Siena 53100</wicri:noRegion></affiliation></author><author><name sortKey="Dougan, Gordan" sort="Dougan, Gordan" uniqKey="Dougan G" first="Gordan" last="Dougan">Gordan Dougan</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Mark J" sort="Walker, Mark J" uniqKey="Walker M" first="Mark J." last="Walker">Mark J. Walker</name><affiliation wicri:level="1"><nlm:aff id="A5">Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072 Queensland</wicri:regionArea><wicri:noRegion>4072 Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Holden, Matthew T G" sort="Holden, Matthew T G" uniqKey="Holden M" first="Matthew T. G." last="Holden">Matthew T. G. Holden</name><affiliation wicri:level="1"><nlm:aff id="A4">The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 15A</wicri:regionArea><wicri:noRegion>Cambridge CB10 15A</wicri:noRegion></affiliation></author><author><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A7">Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Référence des Streptocoques, Hôpitaux Universitaires, Paris Centre Cochin–Hôtel Dieu-Broca, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A14">Institut Cochin, Université Sorbonne Paris Descartes, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Cochin, Université Sorbonne Paris Descartes, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A15">INSERM, U1016, Paris 75014, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1016, Paris 75014</wicri:regionArea><wicri:noRegion>75014</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Glaser, Philippe" sort="Glaser, Philippe" uniqKey="Glaser P" first="Philippe" last="Glaser">Philippe Glaser</name><affiliation wicri:level="1"><nlm:aff id="A1">Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Unité de Biologie des Bacteries Pathogènes à Gram-positif, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">CNRS UMR3525, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR3525, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A3">Institut Pasteur, Bioinformatics platform, Paris 75015, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur, Bioinformatics platform, Paris 75015</wicri:regionArea><wicri:noRegion>75015</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Bacterial Agents (pharmacology)</term><term>Base Sequence</term><term>Clone Cells</term><term>DNA Transposable Elements</term><term>Europe (epidemiology)</term><term>Genes, Bacterial</term><term>Genome, Bacterial</term><term>High-Throughput Nucleotide Sequencing</term><term>Humans</term><term>Molecular Sequence Data</term><term>North America (epidemiology)</term><term>Phylogeny</term><term>Polymorphism, Single Nucleotide</term><term>Selection, Genetic</term><term>Streptococcal Infections (drug therapy)</term><term>Streptococcal Infections (epidemiology)</term><term>Streptococcal Infections (microbiology)</term><term>Streptococcus agalactiae (classification)</term><term>Streptococcus agalactiae (drug effects)</term><term>Streptococcus agalactiae (genetics)</term><term>Streptococcus agalactiae (isolation & purification)</term><term>Tetracycline (pharmacology)</term><term>Tetracycline Resistance (drug effects)</term><term>Tetracycline Resistance (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Amérique du Nord (épidémiologie)</term><term>Antibactériens (pharmacologie)</term><term>Clones cellulaires</term><term>Données de séquences moléculaires</term><term>Europe (épidémiologie)</term><term>Gènes bactériens</term><term>Génome bactérien</term><term>Humains</term><term>Infections à streptocoques (microbiologie)</term><term>Infections à streptocoques (traitement médicamenteux)</term><term>Infections à streptocoques (épidémiologie)</term><term>Phylogénie</term><term>Polymorphisme de nucléotide simple</term><term>Résistance à la tétracycline ()</term><term>Résistance à la tétracycline (génétique)</term><term>Streptococcus agalactiae ()</term><term>Streptococcus agalactiae (génétique)</term><term>Streptococcus agalactiae (isolement et purification)</term><term>Sélection génétique</term><term>Séquence nucléotidique</term><term>Séquençage nucléotidique à haut débit</term><term>Tétracycline (pharmacologie)</term><term>Éléments transposables d'ADN</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Tetracycline</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Europe</term><term>North America</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Streptococcus agalactiae</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Streptococcus agalactiae</term><term>Tetracycline Resistance</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Streptococcal Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Streptococcal Infections</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Streptococcus agalactiae</term><term>Tetracycline Resistance</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Résistance à la tétracycline</term><term>Streptococcus agalactiae</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Streptococcus agalactiae</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Streptococcus agalactiae</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Infections à streptocoques</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Streptococcal Infections</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antibactériens</term><term>Tétracycline</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à streptocoques</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Amérique du Nord</term><term>Europe</term><term>Infections à streptocoques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Base Sequence</term><term>Clone Cells</term><term>DNA Transposable Elements</term><term>Genes, Bacterial</term><term>Genome, Bacterial</term><term>High-Throughput Nucleotide Sequencing</term><term>Humans</term><term>Molecular Sequence Data</term><term>Phylogeny</term><term>Polymorphism, Single Nucleotide</term><term>Selection, Genetic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Clones cellulaires</term><term>Données de séquences moléculaires</term><term>Gènes bactériens</term><term>Génome bactérien</term><term>Humains</term><term>Phylogénie</term><term>Polymorphisme de nucléotide simple</term><term>Résistance à la tétracycline</term><term>Streptococcus agalactiae</term><term>Sélection génétique</term><term>Séquence nucléotidique</term><term>Séquençage nucléotidique à haut débit</term><term>Éléments transposables d'ADN</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P6"><italic>Streptococcus agalactiae</italic> (Group B <italic>Streptococcus</italic>, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and North America during the 1960s. Due to the lack of epidemiological and genomic data, the reasons for this emergence are unknown. Here we show by comparative genome analysis and phylogenetic reconstruction of 229 isolates that the rise of human GBS infections corresponds to the selection and worldwide dissemination of only a few clones. The parallel expansion of the clones is preceded by the insertion of integrative and conjugative elements conferring tetracycline resistance (TcR). Thus, we propose that the use of tetracycline from 1948 onwards led in humans to the complete replacement of a diverse GBS population by only few TcR clones particularly well adapted to their host, causing the observed emergence of GBS diseases in neonates.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Edwards, Ms" uniqKey="Edwards M">MS Edwards</name></author><author><name sortKey="Baker, Cj" uniqKey="Baker C">CJ Baker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edmond, Km" uniqKey="Edmond K">KM Edmond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eickhoff, Tc" uniqKey="Eickhoff T">TC Eickhoff</name></author><author><name sortKey="Klein, Jo" uniqKey="Klein J">JO Klein</name></author><author><name sortKey="Daly, Ak" uniqKey="Daly A">AK Daly</name></author><author><name sortKey="Ingall, D" uniqKey="Ingall D">D Ingall</name></author><author><name 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Thaker</name></author><author><name sortKey="Spanogiannopoulos, P" uniqKey="Spanogiannopoulos P">P Spanogiannopoulos</name></author><author><name sortKey="Wright, Gd" uniqKey="Wright G">GD Wright</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, Ap" uniqKey="Roberts A">AP Roberts</name></author><author><name sortKey="Mullany, P" uniqKey="Mullany P">P Mullany</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Celli, J" uniqKey="Celli J">J Celli</name></author><author><name sortKey="Trieu Cuot, P" uniqKey="Trieu Cuot P">P Trieu-Cuot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arias, Ca" uniqKey="Arias C">CA Arias</name></author><author><name sortKey="Murray, Be" uniqKey="Murray B">BE Murray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davies, J" uniqKey="Davies J">J Davies</name></author><author><name sortKey="Davies, D" uniqKey="Davies D">D Davies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tenover, Fc" uniqKey="Tenover F">FC Tenover</name></author><author><name sortKey="Goering, Rv" uniqKey="Goering R">RV Goering</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Planet, Pj" uniqKey="Planet P">PJ Planet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Willems, Rj" uniqKey="Willems R">RJ Willems</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lebreton, F" uniqKey="Lebreton F">F Lebreton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Durbin, R" uniqKey="Durbin R">R Durbin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tettelin, H" uniqKey="Tettelin H">H Tettelin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glaser, P" uniqKey="Glaser P">P Glaser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darling, Ac" uniqKey="Darling A">AC Darling</name></author><author><name sortKey="Mau, B" uniqKey="Mau B">B Mau</name></author><author><name sortKey="Blattner, Fr" uniqKey="Blattner F">FR Blattner</name></author><author><name sortKey="Perna, Nt" uniqKey="Perna N">NT Perna</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tettelin, H" uniqKey="Tettelin H">H Tettelin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aziz, Rk" uniqKey="Aziz R">RK Aziz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zerbino, Dr" uniqKey="Zerbino D">DR Zerbino</name></author><author><name sortKey="Birney, E" uniqKey="Birney E">E Birney</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosinski Chupin, I" uniqKey="Rosinski Chupin I">I Rosinski-Chupin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lechat, P" uniqKey="Lechat P">P Lechat</name></author><author><name sortKey="Souche, E" uniqKey="Souche E">E Souche</name></author><author><name sortKey="Moszer, I" uniqKey="Moszer I">I Moszer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K Tamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drummond, Aj" uniqKey="Drummond A">AJ Drummond</name></author><author><name sortKey="Rambaut, A" uniqKey="Rambaut A">A Rambaut</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baele, G" uniqKey="Baele G">G Baele</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baele, G" uniqKey="Baele G">G Baele</name></author><author><name sortKey="Lemey, P" uniqKey="Lemey P">P Lemey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drummond, Aj" uniqKey="Drummond A">AJ Drummond</name></author><author><name sortKey="Ho, Sy" uniqKey="Ho S">SY Ho</name></author><author><name sortKey="Phillips, Mj" uniqKey="Phillips M">MJ Phillips</name></author><author><name sortKey="Rambaut, A" uniqKey="Rambaut A">A Rambaut</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luan, Sl" uniqKey="Luan S">SL Luan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manning, Sd" uniqKey="Manning S">SD Manning</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bohnsack, Jf" uniqKey="Bohnsack J">JF Bohnsack</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sadowy, E" uniqKey="Sadowy E">E Sadowy</name></author><author><name sortKey="Matynia, B" uniqKey="Matynia B">B Matynia</name></author><author><name sortKey="Hryniewicz, W" uniqKey="Hryniewicz W">W Hryniewicz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huber, Ca" uniqKey="Huber C">CA Huber</name></author><author><name sortKey="Mcodimba, F" uniqKey="Mcodimba F">F McOdimba</name></author><author><name sortKey="Pflueger, V" uniqKey="Pflueger V">V Pflueger</name></author><author><name sortKey="Daubenberger, Ca" uniqKey="Daubenberger C">CA Daubenberger</name></author><author><name sortKey="Revathi, G" uniqKey="Revathi G">G Revathi</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>Italie</li><li>Royaume-Uni</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Da Cunha, Violette" sort="Da Cunha, Violette" uniqKey="Da Cunha V" first="Violette" last="Da Cunha">Violette Da Cunha</name></region><name sortKey="Bouchier, Christiane" sort="Bouchier, Christiane" uniqKey="Bouchier C" first="Christiane" last="Bouchier">Christiane Bouchier</name><name sortKey="Buchrieser, Carmen" sort="Buchrieser, Carmen" uniqKey="Buchrieser C" first="Carmen" last="Buchrieser">Carmen Buchrieser</name><name sortKey="Buchrieser, Carmen" sort="Buchrieser, Carmen" uniqKey="Buchrieser C" first="Carmen" last="Buchrieser">Carmen Buchrieser</name><name sortKey="Clermont, Dominique" sort="Clermont, Dominique" uniqKey="Clermont D" first="Dominique" last="Clermont">Dominique Clermont</name><name sortKey="Da Cunha, Violette" sort="Da Cunha, Violette" uniqKey="Da Cunha V" first="Violette" last="Da Cunha">Violette Da Cunha</name><name sortKey="Da Cunha, Violette" sort="Da Cunha, Violette" uniqKey="Da Cunha V" first="Violette" last="Da Cunha">Violette Da Cunha</name><name sortKey="Descorps Declere, Stephane" sort="Descorps Declere, Stephane" uniqKey="Descorps Declere S" first="Stéphane" last="Descorps-Declere">Stéphane Descorps-Declere</name><name sortKey="Dmytruk, Nicolas" sort="Dmytruk, Nicolas" uniqKey="Dmytruk N" first="Nicolas" last="Dmytruk">Nicolas Dmytruk</name><name sortKey="Douarre, Pierre Emmanuel" sort="Douarre, Pierre Emmanuel" uniqKey="Douarre P" first="Pierre-Emmanuel" last="Douarre">Pierre-Emmanuel Douarre</name><name sortKey="Douarre, Pierre Emmanuel" sort="Douarre, Pierre Emmanuel" uniqKey="Douarre P" first="Pierre-Emmanuel" last="Douarre">Pierre-Emmanuel Douarre</name><name sortKey="Glaser, Philippe" sort="Glaser, Philippe" uniqKey="Glaser P" first="Philippe" last="Glaser">Philippe Glaser</name><name sortKey="Glaser, Philippe" sort="Glaser, Philippe" uniqKey="Glaser P" first="Philippe" last="Glaser">Philippe Glaser</name><name sortKey="Glaser, Philippe" sort="Glaser, Philippe" uniqKey="Glaser P" first="Philippe" last="Glaser">Philippe Glaser</name><name sortKey="Lechat, Pierre" sort="Lechat, Pierre" uniqKey="Lechat P" first="Pierre" last="Lechat">Pierre Lechat</name><name sortKey="Lopez Sanchez, Maria Jose" sort="Lopez Sanchez, Maria Jose" uniqKey="Lopez Sanchez M" first="Maria-José" last="Lopez-Sanchez">Maria-José Lopez-Sanchez</name><name sortKey="Lopez Sanchez, Maria Jose" sort="Lopez Sanchez, Maria Jose" uniqKey="Lopez Sanchez M" first="Maria-José" last="Lopez-Sanchez">Maria-José Lopez-Sanchez</name><name sortKey="Ma, Laurence" sort="Ma, Laurence" uniqKey="Ma L" first="Laurence" last="Ma">Laurence Ma</name><name sortKey="Moszer, Ivan" sort="Moszer, Ivan" uniqKey="Moszer I" first="Ivan" last="Moszer">Ivan Moszer</name><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><name sortKey="Poyart, Claire" sort="Poyart, Claire" uniqKey="Poyart C" first="Claire" last="Poyart">Claire Poyart</name><name sortKey="Rosinski Chupin, Isabelle" sort="Rosinski Chupin, Isabelle" uniqKey="Rosinski Chupin I" first="Isabelle" last="Rosinski-Chupin">Isabelle Rosinski-Chupin</name><name sortKey="Rosinski Chupin, Isabelle" sort="Rosinski Chupin, Isabelle" uniqKey="Rosinski Chupin I" first="Isabelle" last="Rosinski-Chupin">Isabelle Rosinski-Chupin</name><name sortKey="Sauvage, Elisabeth" sort="Sauvage, Elisabeth" uniqKey="Sauvage E" first="Elisabeth" last="Sauvage">Elisabeth Sauvage</name><name sortKey="Sauvage, Elisabeth" sort="Sauvage, Elisabeth" uniqKey="Sauvage E" first="Elisabeth" last="Sauvage">Elisabeth Sauvage</name><name sortKey="Souche, Erika" sort="Souche, Erika" uniqKey="Souche E" first="Erika" last="Souche">Erika Souche</name><name sortKey="Spinali, Sebastien" sort="Spinali, Sebastien" uniqKey="Spinali S" first="Sebastien" last="Spinali">Sebastien Spinali</name><name sortKey="Tichit, Magali" sort="Tichit, Magali" uniqKey="Tichit M" first="Magali" last="Tichit">Magali Tichit</name><name sortKey="Trieu Cuot, Patrick" sort="Trieu Cuot, Patrick" uniqKey="Trieu Cuot P" first="Patrick" last="Trieu-Cuot">Patrick Trieu-Cuot</name><name sortKey="Trieu Cuot, Patrick" sort="Trieu Cuot, Patrick" uniqKey="Trieu Cuot P" first="Patrick" last="Trieu-Cuot">Patrick Trieu-Cuot</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Davies, Mark R" sort="Davies, Mark R" uniqKey="Davies M" first="Mark R." last="Davies">Mark R. Davies</name></noRegion><name sortKey="Dougan, Gordan" sort="Dougan, Gordan" uniqKey="Dougan G" first="Gordan" last="Dougan">Gordan Dougan</name><name sortKey="Holden, Matthew T G" sort="Holden, Matthew T G" uniqKey="Holden M" first="Matthew T. G." last="Holden">Matthew T. G. Holden</name><name sortKey="Parkhill, Julian" sort="Parkhill, Julian" uniqKey="Parkhill J" first="Julian" last="Parkhill">Julian Parkhill</name></country><country name="Australie"><noRegion><name sortKey="Davies, Mark R" sort="Davies, Mark R" uniqKey="Davies M" first="Mark R." last="Davies">Mark R. Davies</name></noRegion><name sortKey="Mcmillan, David J" sort="Mcmillan, David J" uniqKey="Mcmillan D" first="David J." last="Mcmillan">David J. Mcmillan</name><name sortKey="Mcmillan, David J" sort="Mcmillan, David J" uniqKey="Mcmillan D" first="David J." last="Mcmillan">David J. Mcmillan</name><name sortKey="Walker, Mark J" sort="Walker, Mark J" uniqKey="Walker M" first="Mark J." last="Walker">Mark J. Walker</name></country><country name="Italie"><noRegion><name sortKey="Margarit, Immaculada" sort="Margarit, Immaculada" uniqKey="Margarit I" first="Immaculada" last="Margarit">Immaculada Margarit</name></noRegion><name sortKey="Maione, Domenico" sort="Maione, Domenico" uniqKey="Maione D" first="Domenico" last="Maione">Domenico Maione</name><name sortKey="Perkins, Tim" sort="Perkins, Tim" uniqKey="Perkins T" first="Tim" last="Perkins">Tim Perkins</name><name sortKey="Romi, Benedetta" sort="Romi, Benedetta" uniqKey="Romi B" first="Benedetta" last="Romi">Benedetta Romi</name><name sortKey="Telford, John L" sort="Telford, John L" uniqKey="Telford J" first="John L." last="Telford">John L. Telford</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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